Commercial buildings and educational facilities should conduct baseline indoor air quality testing annually, with additional testing when occupants report health complaints, after renovations or construction work, or when HVAC systems are modified. Schools face particular obligations to protect children who are more vulnerable to air quality impacts on development and learning. Healthcare facilities, childcare centers, and senior living facilities require more frequent monitoring due to vulnerable populations. Many insurance companies require air quality documentation for liability protection, while OSHA and local health departments may mandate testing for certain facility types. Regular testing helps facility managers identify problems before they impact occupant health and demonstrates compliance with workplace safety standards.